In-Gel Tryptic Digestion Kit
6776
0089871 NCI9871
2/5/2004
7/3/2003
Kit Material Safety Data Sheet(s)
Common Name
Supplier
Manufacturer
Code
MSDS#
Validation Date
Print Date
In Case of Emergency
Chemical Product and Company Identification
Responsible Name Pierce Administration
CHEMTREC:
800.424.9300
OUTSIDE US:
202.483.7616
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
USA
815.968.0747 or
1.800.874.3723
Pierce Milwaukee LLC
2202 N. Bartlett Avenue
Milwaukee, WI 53202-1009
USA
1.877.886.7629
Classification (USA)
Classification (Europe)
Material
Safety Data
Sheet
Safety documents for kit components are available upon
request by phone (1-800-874-3723) as well as on the
Internet at http://www.piercenet.com.
Common Name
Code
Classification
Code
Common Name
Classification
89871A
Trypsin, Modified
Xn
89871B
Trypsin Storage Solution
--
89871C
Acetonitrile
F, T
89871D
Ammonium Bicarbonate
Xn
89871E
TCEP
C
89871F
Iodoacetamide
T
89871A
Trypsin, Modified
Sensitizing substance.
89871B
Trypsin Storage Solution
--
89871C
Acetonitrile
Flammable liquid having
a flash point lower than
37.8°C (100°F).
Toxic.
Irritating substance.
89871D
Ammonium Bicarbonate
Irritating substance.
89871E
TCEP
89871F
Iodoacetamide
Toxic.
Sensitizing substance.
Eng
Conforms to 93/112/EC and ISO 11014-1
Material Safety Data Sheet
Acetonitrile
6772
89871C
In USA:
In Europe:
Pierce
Perbio Science
P.O. Box 117
Industriezone III
Rockford, IL 61105 Industrielaan 27
USA
9320 Erembodegem-Aalst
815.968.0747 or
Belgium
1.800.874.3723
Tel:+32 53 83 44 04

Fax:+32 53 83 76 38
CALL CHEMTREC:
800.424.9300
OUTSIDE US:
202.483.7616
Pierce Milwaukee LLC
2202 N. Bartlett Avenue
Milwaukee, WI 53202-1009
USA
1.877.886.7629
7/25/2003
7/25/2003
Product name
Supplier
Manufacturer
Product No.
MSDS#
Validation Date
Print Date
In Case of Emergency
Section 1. Chemical Product and Company Identification
Responsible Name Pierce Administration
Synonyms ACETONITRIL (GERMAN, DUTCH); ACETONITRILE ; CYANOMETHANE; CYANURE DE METHYL (FRENCH);
ETHANENITRILE; ETHYL NITRILE; METHANECARBONITRILE; METHANE, CYANO-; METHYL CYANIDE;
NCI-C60822; USAF EK-488
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Eng
1) Acetonitrile
75-05-8
98-100
200-835-2
F, T
R11, R23/24/25
Ingredient Name
EC Number
CAS No.
R-Phrases
Substance/Preparation
Substance
%
Symbol
:
Section 2. Composition, Information on Ingredients
Absorbed through skin. Eye contact. Inhalation. Ingestion.
Emergency Overview
Medical Conditions Aggravated
by Overexposure:
Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or
many human organs.
Not available.
Overexposure /Signs/Symptoms
Section 3. Hazards Identification
Routes of Entry
Potential Acute Health Effects
Carcinogenic Effects Data
Keep away from heat, sparks and flame. Avoid contact with eyes, skin and clothing. Do not ingest. Avoid breathing
vapor or mist. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling.
Very hazardous in case of eye contact (irritant). Hazardous in case of skin contact (irritant). Slightly hazardous in case
of skin contact (permeator), of ingestion, of inhalation (lung irritant). Severe over-exposure can result in death.
Inflammation of the eye is characterized by redness, watering, and itching.
CARCINOGENIC EFFECTS: Classified None. by NIOSH. A4 (Not classifiable for human or animal.) by ACGIH.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
WARNING!
HIGHLY FLAMMABLE LIQUID AND VAPOR.
VAPOR MAY CAUSE FLASH FIRE.
HARMFUL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED.
CAUSES SEVERE EYE IRRITATION.
CAUSES DAMAGE TO THE FOLLOWING ORGANS: KIDNEYS, LIVER, MUCOUS
MEMBRANES, CARDIOVASCULAR SYSTEM, RESPIRATORY TRACT, SKIN, EYES,
CENTRAL NERVOUS SYSTEM, EYE, LENS OR CORNEA.
MAY CAUSE SKIN IRRITATION.
United States
Continued on Next Page
Acetonitrile
Page: 2/6
Physical/chemical hazards
Human health hazards
Environmental hazards Not applicable.
Toxic by inhalation, in contact with skin and if swallowed.
Highly flammable.
See Toxicological Information (section 11)
Classification R11, R23/24/25
Europe
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately.
Skin Contact
Ingestion
Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping
eyelids open. Cold water may be used. Get medical attention immediately.
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing
and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse. Thoroughly
clean shoes before reuse. Get medical attention immediately.
May be fatal if inhaled.
May be fatal if swallowed.
Hazardous in case of skin contact (irritant). Slightly hazardous in case of skin contact (permeator). Severe over-exposure
can result in death. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering.
Skin Contact
Very hazardous in case of eye contact (irritant). Inflammation of the eye is characterized by redness, watering, and itching.
Eye Contact
Inhalation
Aggravating conditions Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many
human organs.
First-Aid Measures
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention immediately.
Notes to Physician Not available.
Not available.
Protection of first-aiders
Ingestion
Effects and symptoms
Inhalation
Eye Contact
Section 4. First Aid Measures
Notice to Reader Get immediate medical attention.
Hazardous thermal (de)composition
products
Not available.
Flammable.
CLOSED CUP: 5.9°C (42.6°F). OPEN CUP: 5.6°C (42.1°F) (Cleveland).
Flammable liquid, soluble or dispersed in water.
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use alcohol foam, water spray or fog.
Highly flammable in presence of open flames and sparks, of heat, of oxidizing materials.
Store under nitrogen.
Section 5. Fire Fighting Measures
Flammability of the Product
Flash Points
Fire Hazards in Presence of Various
Substances
Fire Fighting Media
and Instructions
Special Remarks on Fire Hazards
Be sure to use an approved/certified respirator or equivalent.
Protective Clothing (Fire)
Continued on Next Page
Acetonitrile
Page: 3/6
Flammable liquid. Poisonous liquid.
Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth, sand or
other non-combustible material. Do not get water inside container. Do not touch spilled material. Use water spray to
reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Call for assistance on
disposal. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDS and
with local authorities.
Section 6. Accidental Release Measures
Small Spill and Leak Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container.
Environmental Precautions and
Clean-up Methods
Personal precautions Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly
closed and sealed until ready for use. Avoid all possible sources of ignition (spark or flame).
Keep away from heat, sparks and flame. Keep container closed. Use only with adequate ventilation. To avoid fire or
explosion, dissipate static electricity during transfer by grounding and bonding containers and equipment before
transferring material. Use explosion-proof electrical (ventilating, lighting and material handling) equipment.
Section 7. Handling and Storage
Handling
Storage
Suitable / Not suitable
Packaging materials
Use original container.
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
1) Acetonitrile
TWA: 40 STEL: 60 CEIL: 160 (ppm) from BAuA [Germany] [1999] SKIN
Germany
1) Acetonitrile
TWA: 40 (ppm) from Arbeidsinspectie [Netherlands] [2000] Inhalation
Netherlands
1) Acetonitrile
TWA: 40 (ppm) from INRS [France] [1999] SKIN
France
1) Acetonitrile
TWA: 30 STEL: 105 (ppm) from Arbeidstilsynet [Norway] [1996] Inhalation
Norway
1) Acetonitrile
TWA: 40 (ppm) from Arbejdstilsynet [Denmark] [1996] Inhalation
Denmark
1) Acetonitrile
TWA: 30 STEL: 100 CEIL: 60 (ppm) from AFS [Sweden] [1996] Inhalation
Sweden
1) Acetonitrile
TWA: 40 STEL: 60 (ppm) from ACGIH (TLV) [United States] [2000] Inhalation
TWA: 40 STEL: 60 (ppb) from OSHA (PEL) [United States] [1989] Inhalation
United States
Ingredient Name
Occupational Exposure Limits
Engineering Controls Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station
location.
Section 8. Exposure Controls/Personal Protection
Exposure Limit Values
Personal Protection
Eyes
Body Lab coat.
Splash goggles.
Continued on Next Page
Acetonitrile
Page: 4/6
Hands
Protective Clothing
(Pictograms)
Gloves.
Respiratory Respirator is not needed under normal and intended conditions of use, if exposures are kept below established limits.
81.72°C (179.1°F)
Liquid.
7 [Neutral.]
-41.85°C (-43.3°F)
0.787 (Water = 1)
1.42 (Air = 1)
9.7 kPa (@ 20°C)
See solubility in water, methanol.
Soluble in cold water, hot water, methanol.
40 ppm
274.8°C (526.6°F)
41.05 g/mole
Ethereal.
COLORLESS LIQUID WITH A SWEET,
ETHER-LIKE ODOR [NOTE:FORMS
CYANIDE IN THE BODY] Sweet.
Colorless.
Boiling/Condensation Point
Melting/Freezing Point
2.33 compared to (n-BUTYL ACETATE=1)
Dynamic: 0.35 cP
Physical State and
Appearance
Molecular Weight
pH (1% Soln/Water)
Critical Temperature
Specific Gravity
Vapor Pressure
Vapor Density
Odor Threshold
Evaporation Rate
Viscosity
Dispersion Properties
Solubility
Odor
Taste
Color
Section 9. Physical and Chemical Properties
The product is stable.
Reactive with oxidizing agents, acids, moisture.
Slightly reactive to reactive with reducing agents, alkalis.
Will not occur.
Not available.
Section 10. Stability and Reactivity
Stability and Reactivity
Conditions to avoid
Materials to avoid
Hazardous Polymerization
Hazardous Decomposition
Products
Not available.
Acute oral toxicity (LD50): 50 mg/kg [Rabbit].
Acute dermal toxicity (LD50): 982 mg/kg [Rabbit.].
Acute toxicity of the vapor (LC50): 16000 ppm 4 hours [Rat.].
Slightly hazardous in case of ingestion, of inhalation (lung irritant).
CARCINOGENIC EFFECTS: Classified None. by NIOSH. A4 (Not classifiable for human or animal.) by ACGIH.
Causes damage to the following organs: kidneys, liver, mucous membranes, cardiovascular system, upper respiratory tract,
skin, eyes, central nervous system (CNS), eye, lens or cornea.
Not available.
Section 11. Toxicological Information
Toxicity to Animals
Chronic Effects on Humans
Other Toxic Effects on Humans
Special Remarks on Toxicity to
Animals
Continued on Next Page
Acetonitrile
Page: 5/6
Material is irritating to mucous membranes and upper respiratory tract.
Not available.
Special Remarks on Chronic
Effects on Humans
Special Remarks on Other Toxic
Effects on Humans
Ecotoxicity Not available.
Mobility
Germany water class
Not available.
Not available.
Not available.
Persistence/degradability
Bioaccumulative potential
VCI WGK: No products were found.
Section 12. Ecological Information
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Not available.
Waste Information
Waste Stream
Section 13. Disposal Considerations
Consult your local or regional authorities.
Contact the supplier for all information regarding the proper transportation method for this material.
Section 14. Transport Information
U.S. Federal Regulations
Flammable liquid having a flash point lower than 37.8°C (100°F).
Toxic.
Irritating substance.
Warning: This product contains a chemical known to the State of California to cause cancer.
HCS Classification
Section 15. Regulatory Information
TSCA 8(a) PAIR: Acetonitrile
TSCA 8(b) inventory: Acetonitrile
TSCA 8(c) calls for record of SAR: Acetonitrile
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Acetonitrile
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Acetonitrile: fire, immediate health hazard, delayed health hazard
R11- Highly flammable.
R23/24/25- Toxic by inhalation, in contact with skin and if swallowed.
S16- Keep away from sources of ignition - No smoking.
S27- Take off immediately all contaminated clothing.
S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where
possible).
Highly flammable, Toxic
Label Requirements
(Europe)
1
Continued on Next Page
Acetonitrile
Page: 6/6
Pennsylvania RTK: Acetonitrile: (environmental hazard, generic environmental hazard)
Massachusetts RTK: Acetonitrile
New Jersey: Acetonitrile
California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which
would require a warning under the statute: Acetonitrile
Clean Water Act (CWA) 307: Acetonitrile
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
State Regulations
CEPA DSL: Acetonitrile
Australia (NICNAS): Acetonitrile
Germany water class: Acetonitrile
VCI WGK: No products were found.
Korea (TCCL): Acetonitrile
Philippines (RA6969): Acetonitrile
WHMIS (Canada) CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F).
CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC).
R11- Highly flammable.
R23/24/25- Toxic by inhalation, in contact with skin and if swallowed.
DSCL (EEC)
International Regulations
Not available.
EINECS
International Lists
SARA 313 toxic chemical notification and release reporting: Acetonitrile
Version
2.01
Date of Previous Issue
7/23/2003
-SAX, N.I. Dangerous Properties of Industrial Materials. Toronto, Van Nostrand Reinold, 6e ed. 1984. -The
Sigma-Aldrich Library of Chemical Safety Data, Edition II.
Section 16. Other Information
References
Validated by Pierce Administration on 7/25/2003.
Verified by Pierce Administration.
Printed 7/25/2003.
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any
liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution.
Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
Hazardous Material
Information System
(U.S.A.)
2
3
0
h
0
3
2
*
National Fire Protection
Association (U.S.A.)
Health
Specific Hazard
Reactivity
Fire Hazard
Health
Fire Hazard
Reactivity
Personal Protection
History of Document Changes Any information changes since last document version are marked with a triangle symbol.
Toxic by inhalation, in contact with skin and if swallowed.
Full text of R-Phrases
referenced under headings 2 and 3:
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Conforms to 93/112/EC and ISO 11014-1
Material Safety Data Sheet
Iodoacetamide
6775
89871F
In USA:
In Europe:
Pierce
Perbio Science
P.O. Box 117
Industriezone III
Rockford, IL 61105 Industrielaan 27
USA
9320 Erembodegem-Aalst
815.968.0747 or
Belgium
1.800.874.3723
Tel:+32 53 83 44 04

Fax:+32 53 83 76 38
CALL CHEMTREC:
800.424.9300
OUTSIDE US:
202.483.7616
Pierce Milwaukee LLC
2202 N. Bartlett Avenue
Milwaukee, WI 53202-1009
USA
1.877.886.7629
7/3/2003
7/3/2003
Product name
Supplier
Manufacturer
Product No.
MSDS#
Validation Date
Print Date
In Case of Emergency
Section 1. Chemical Product and Company Identification
Responsible Name Pierce Administration
Synonyms
IODOACETAMIDE; ALPHA-IODOACETAMIDE; 2-IODOACETAMIDE; MONOIODOACETAMIDE; SURAUTO; USAF
D-1
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Eng
1) Iodoacetamide
144-48-9
98-100
205-630-1
T
R23/24/25, R42/43,
R61
Ingredient Name
EC Number
CAS No.
R-Phrases
Substance/Preparation
Substance
%
Symbol
:
Section 2. Composition, Information on Ingredients
Absorbed through skin. Eye contact. Inhalation. Ingestion.
Emergency Overview
Medical Conditions Aggravated
by Overexposure:
Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or
many human organs.
Not available.
Overexposure /Signs/Symptoms
Section 3. Hazards Identification
Routes of Entry
Potential Acute Health Effects
Carcinogenic Effects Data
Avoid contact with eyes, skin and clothing. Do not ingest. Do not breathe dust. Avoid prolonged or repeated contact
with skin. Keep container closed. Use only with adequate ventilation. Avoid exposure during pregnancy. Wash
thoroughly after handling.
Hazardous in case of skin contact (sensitizer), of inhalation (lung sensitizer). Severe over-exposure can result in
death.
CARCINOGENIC EFFECTS: Classified None. by NIOSH.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
WARNING!
HARMFUL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED.
CAUSES DAMAGE TO THE FOLLOWING ORGANS: MUCOUS MEMBRANES, SKIN,
EYES, thyroid.
POSSIBLE BIRTH DEFECT HAZARD.
CONTAINS MATERIAL WHICH MAY CAUSE BIRTH DEFECTS BASED ON ANIMAL
DATA.
MAY CAUSE ALLERGIC RESPIRATORY AND SKIN REACTION.
United States
Europe
Continued on Next Page
Iodoacetamide
Page: 2/6
Physical/chemical hazards
Human health hazards
Environmental hazards Not applicable.
Toxic by inhalation, in contact with skin and if swallowed.
May cause sensitization by inhalation and skin contact.
May cause harm to the unborn child.
Not applicable.
See Toxicological Information (section 11)
Classification R23/24/25, R42/43, R61
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately.
Skin Contact
Ingestion
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical attention.
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately.
May be fatal if inhaled.
May be fatal if swallowed.
Hazardous in case of skin contact (sensitizer). Severe over-exposure can result in death.
Skin Contact
Not available.
Eye Contact
Inhalation
Aggravating conditions Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many
human organs.
First-Aid Measures
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention immediately.
Notes to Physician Not available.
Not available.
Protection of first-aiders
Ingestion
Effects and symptoms
Inhalation
Eye Contact
Section 4. First Aid Measures
Notice to Reader Get immediate medical attention.
Hazardous thermal (de)composition
products
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.
May be combustible at high temperature.
Not available.
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Not available.
Section 5. Fire Fighting Measures
Flammability of the Product
Flash Points
Fire Hazards in Presence of Various
Substances
Fire Fighting Media
and Instructions
Be sure to use an approved/certified respirator or equivalent.
Protective Clothing (Fire)
Poisonous solid.
Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to reduce
vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition sources. Call for
assistance on disposal.
Section 6. Accidental Release Measures
Small Spill and Leak Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Environmental Precautions and
Clean-up Methods
Personal precautions Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Continued on Next Page
Iodoacetamide
Page: 3/6
Keep container tightly closed. Keep container in a cool, well-ventilated area.
Avoid contact with eyes, skin, and clothing. Do not ingest. Do not breathe dust. Avoid prolonged or repeated contact
with skin. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling.
Section 7. Handling and Storage
Handling
Storage
Suitable / Not suitable
Packaging materials
Use original container.
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
1) Iodoacetamide
Not available.
Germany
1) Iodoacetamide
Not available.
Netherlands
1) Iodoacetamide
Not available.
France
1) Iodoacetamide
Not available.
Norway
1) Iodoacetamide
Not available.
Denmark
1) Iodoacetamide
Not available.
Sweden
1) Iodoacetamide
Not available.
United States
Ingredient Name
Occupational Exposure Limits
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Section 8. Exposure Controls/Personal Protection
Exposure Limit Values
Personal Protection
Eyes
Body
Hands
Protective Clothing
(Pictograms)
Gloves.
Lab coat.
Splash goggles.
Respiratory Respirator is not needed under normal and intended conditions of use, if exposures are kept below established limits.
Continued on Next Page
Iodoacetamide
Page: 4/6
Solid.
93.06 to 96.06°C (199.5 to 204.9°F)
Not available.
Not available.
184.97 g/mole
Not available.
Not available.
Not available.
Melting/Freezing Point
Physical State and
Appearance
Molecular Weight
Dispersion Properties
Solubility
Odor
Taste
Color
C2 H4 I N O
Molecular Formula
Section 9. Physical and Chemical Properties
The product is stable.
Reactive with oxidizing agents, reducing agents, acids, alkalis.
Will not occur.
Not available.
Section 10. Stability and Reactivity
Stability and Reactivity
Conditions to avoid
Materials to avoid
Hazardous Polymerization
Hazardous Decomposition
Products
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.
Acute oral toxicity (LD50): 74 mg/kg [Mouse].
Hazardous in case of inhalation (lung sensitizer).
CARCINOGENIC EFFECTS: Classified None. by NIOSH.
Causes damage to the following organs: mucous membranes, skin, eyes, thyroid.
Not available.
Not available.
Not available.
Section 11. Toxicological Information
Toxicity to Animals
Chronic Effects on Humans
Other Toxic Effects on Humans
Special Remarks on Toxicity to
Animals
Special Remarks on Chronic
Effects on Humans
Special Remarks on Other Toxic
Effects on Humans
Ecotoxicity Not available.
Mobility
Germany water class
Not available.
Not available.
Not available.
Persistence/degradability
Bioaccumulative potential
VCI WGK: No products were found.
Section 12. Ecological Information
Continued on Next Page
Iodoacetamide
Page: 5/6
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Not available.
Waste Information
Waste Stream
Section 13. Disposal Considerations
Consult your local or regional authorities.
Contact the supplier for all information regarding the proper transportation method for this material.
Section 14. Transport Information
U.S. Federal Regulations
Toxic.
Sensitizing substance.
HCS Classification
Section 15. Regulatory Information
TSCA 8(b) inventory: Iodoacetamide
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
CEPA DSL: Iodoacetamide
WHMIS (Canada) CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
R23/24/25- Toxic by inhalation, in contact with skin and if swallowed.
R42/43- May cause sensitization by inhalation and skin contact.
R61- May cause harm to the unborn child.
DSCL (EEC)
International Regulations
Not available.
EINECS
International Lists
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Iodoacetamide
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Iodoacetamide: delayed health hazard
SARA 313 toxic chemical notification and release reporting: No products were found.
R23/24/25- Toxic by inhalation, in contact with skin and if swallowed.
R42/43- May cause sensitization by inhalation and skin contact.
R61- May cause harm to the unborn child.
S22- Do not breathe dust.
S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39- Wear suitable protective clothing, gloves and eye/face protection.
S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where
possible).
Toxic
Label Requirements
(Europe)
1
Continued on Next Page
Iodoacetamide
Page: 6/6
No products were found.
California prop. 65: No products were found.
State Regulations
Australia (NICNAS): Iodoacetamide
VCI WGK: No products were found.
Korea (TCCL): Iodoacetamide
Philippines (RA6969): Iodoacetamide
Version
1
Date of Previous Issue No Previous
Validation
Not available.
Section 16. Other Information
References
Validated by Pierce Administration on 7/3/2003.
Verified by Pierce Administration.
Printed 7/3/2003.
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any
liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution.
Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
Hazardous Material
Information System
(U.S.A.)
2
0
0
E
0
0
2
*
National Fire Protection
Association (U.S.A.)
Health
Specific Hazard
Reactivity
Fire Hazard
Health
Fire Hazard
Reactivity
Personal Protection
History of Document Changes Any information changes since last document version are marked with a triangle symbol.
Toxic by inhalation, in contact with skin and if swallowed.
May cause sensitization by inhalation and skin contact.
May cause harm to the unborn child.
Full text of R-Phrases
referenced under headings 2 and 3:
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Conforms to 93/112/EC and ISO 11014-1
Material Safety Data Sheet
Trypsin Storage Solution
6771
89871B
In USA:
In Europe:
Pierce
Perbio Science
P.O. Box 117
Industriezone III
Rockford, IL 61105 Industrielaan 27
USA
9320 Erembodegem-Aalst
815.968.0747 or
Belgium
1.800.874.3723
Tel:+32 53 83 44 04

Fax:+32 53 83 76 38
CALL CHEMTREC:
800.424.9300
OUTSIDE US:
202.483.7616
Pierce Milwaukee LLC
2202 N. Bartlett Avenue
Milwaukee, WI 53202-1009
USA
1.877.886.7629
7/3/2003
7/3/2003
Product name
Supplier
Manufacturer
Product No.
MSDS#
Validation Date
Print Date
In Case of Emergency
Section 1. Chemical Product and Company Identification
Responsible Name Pierce Administration
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Eng
No hazardous ingredient according to 29 CFR 1910.1200 Hazard Communication Standard (USA) and Directives 1999/45/EC-2001/59/EC (EU)
Ingredient Name
EC Number
CAS No.
R-Phrases
Substance/Preparation
Preparation
%
Symbol
:
Section 2. Composition, Information on Ingredients
Physical/chemical hazards
Human health hazards
Environmental hazards Not applicable.
Not applicable.
Not applicable.
Absorbed through skin. Eye contact. Inhalation. Ingestion.
Emergency Overview
Medical Conditions Aggravated
by Overexposure:
Repeated or prolonged exposure is not known to aggravate medical condition.
Not available.
Overexposure /Signs/Symptoms
Section 3. Hazards Identification
Routes of Entry
Potential Acute Health Effects
Carcinogenic Effects Data
See Toxicological Information (section 11)
Do not get in eyes. Avoid breathing vapor or mist. Keep container closed. Use only with adequate ventilation. Wash
thoroughly after handling.
Non-irritant for skin. Non-sensitizer for skin. Non-irritating to the eyes. Non-hazardous in case of ingestion.
Non-hazardous in case of inhalation. Non-irritant for lungs. Non-sensitizer for lungs.
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
No specific hazard.
Classification Not controlled under dsd (Europe).
United States
Europe
Continued on Next Page
Trypsin Storage Solution
Page: 2/6
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a
collar, tie, belt or waistband.
Skin Contact
Ingestion
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Cold water may be used. Get medical attention if irritation occurs.
Wash with soap and water. Get medical attention if irritation develops. Cold water may be used.
Non-hazardous in case of inhalation. Non-irritant for lungs. Non-sensitizer for lungs.
Non-hazardous in case of ingestion.
Non-irritant for skin. Non-sensitizer for skin.
Skin Contact
Non-irritating to the eyes.
Eye Contact
Inhalation
Aggravating conditions Repeated or prolonged exposure is not known to aggravate medical condition.
First-Aid Measures
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention if symptoms appear.
Notes to Physician Not available.
Not available.
Protection of first-aiders
Ingestion
Effects and symptoms
Inhalation
Eye Contact
Section 4. First Aid Measures
Hazardous thermal (de)composition
products
Not applicable.
Non-flammable.
Not applicable.
Not applicable.
Not applicable.
Section 5. Fire Fighting Measures
Flammability of the Product
Flash Points
Fire Hazards in Presence of Various
Substances
Fire Fighting Media
and Instructions
Not applicable.
Protective Clothing (Fire)
Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading
water on the contaminated surface and allow to evacuate through the sanitary system.
Section 6. Accidental Release Measures
Small Spill and Leak Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container.
Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Environmental Precautions and
Clean-up Methods
Personal precautions Safety glasses. Lab coat.
Keep container tightly closed. Keep container in a cool, well-ventilated area.
After handling, always wash hands thoroughly with soap and water.
Section 7. Handling and Storage
Handling
Storage
Suitable / Not suitable
Packaging materials
Use original container.
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Continued on Next Page
Trypsin Storage Solution
Page: 3/6
Germany
Netherlands
France
Norway
Denmark
Sweden
United States
Ingredient Name
Occupational Exposure Limits
Engineering Controls Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective threshold limit value.
Section 8. Exposure Controls/Personal Protection
Exposure Limit Values
Personal Protection
Eyes
Body
Protective Clothing
(Pictograms)
Safety glasses.
Lab coat.
The lowest known value is 100°C (212°F) (Milli-Q Water).
Liquid.
<7
May start to solidify at -0.1°C (31.8°F) based on data for: Milli-Q Water.
The only known value is 1 (Water = 1) (Milli-Q Water).
The highest known value is 0.62 (Air = 1) (Milli-Q Water).
The highest known value is 2.3 kPa (@ 20°C) (Milli-Q Water).
See solubility in water.
Easily soluble in cold water.
Not applicable.
Odorless.
Not available.
Clear
Boiling/Condensation Point
Melting/Freezing Point
0.36 (Milli-Q Water) compared to Butyl acetate.
Physical State and
Appearance
Molecular Weight
pH (1% Soln/Water)
Specific Gravity
Vapor Pressure
Vapor Density
Evaporation Rate
Dispersion Properties
Solubility
Odor
Taste
Color
Section 9. Physical and Chemical Properties
Continued on Next Page
Trypsin Storage Solution
Page: 4/6
The product is stable.
Not available.
Will not occur.
Not available.
Section 10. Stability and Reactivity
Stability and Reactivity
Conditions to avoid
Materials to avoid
Hazardous Polymerization
Hazardous Decomposition
Products
Not applicable.
LD50: Not available.
LC50: Not available.
Non-irritating to the eyes. Non-hazardous in case of ingestion. Non-hazardous in case of inhalation. Non-irritant for lungs.
Non-sensitizer for lungs. Non-corrosive to the eyes. Non-corrosive for lungs.
Not available.
Not available.
Not available.
Not available.
Section 11. Toxicological Information
Toxicity to Animals
Chronic Effects on Humans
Other Toxic Effects on Humans
Special Remarks on Toxicity to
Animals
Special Remarks on Chronic
Effects on Humans
Special Remarks on Other Toxic
Effects on Humans
Ecotoxicity Not available.
Mobility
Germany water class
Not available.
Not available.
Not available.
Persistence/degradability
Bioaccumulative potential
VCI WGK: No products were found.
Section 12. Ecological Information
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Not available.
Waste Information
Waste Stream
Section 13. Disposal Considerations
Consult your local or regional authorities.
Contact the supplier for all information regarding the proper transportation method for this material.
Section 14. Transport Information
Continued on Next Page
Trypsin Storage Solution
Page: 5/6
U.S. Federal Regulations
No products were found.
--
HCS Classification
Section 15. Regulatory Information
California prop. 65: No products were found.
TSCA 8(b) inventory: Milli-Q Water
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
State Regulations
CEPA DSL: Milli-Q Water
Australia (NICNAS): Milli-Q Water
VCI WGK: No products were found.
Korea (TCCL): Milli-Q Water
Philippines (RA6969): Milli-Q Water
WHMIS (Canada) Not controlled under WHMIS (Canada).
This product is not classified according to the EU regulations.
DSCL (EEC)
International Regulations
Not available.
EINECS
International Lists
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found.
SARA 313 toxic chemical notification and release reporting: No products were found.
This product is not classified according to the EU regulations.
Label Requirements
(Europe)
1
Date of Previous Issue No Previous
Validation
Not available.
Section 16. Other Information
References
Validated by Pierce Administration on 7/3/2003.
Verified by Pierce Administration.
Hazardous Material
Information System
(U.S.A.)
0
0
0
a
0
0
0
National Fire Protection
Association (U.S.A.)
Health
Specific Hazard
Reactivity
Fire Hazard
Health
Fire Hazard
Reactivity
Personal Protection
History of Document Changes Any information changes since last document version are marked with a triangle symbol.
No hazardous ingredient.
Full text of R-Phrases
referenced under headings 2 and 3:
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Continued on Next Page
Trypsin Storage Solution
Page: 6/6
Version
1
Printed 7/3/2003.
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any
liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution.
Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
Conforms to 93/112/EC and ISO 11014-1
Material Safety Data Sheet
TCEP
6774
89871E
In USA:
In Europe:
Pierce
Perbio Science
P.O. Box 117
Industriezone III
Rockford, IL 61105 Industrielaan 27
USA
9320 Erembodegem-Aalst
815.968.0747 or
Belgium
1.800.874.3723
Tel:+32 53 83 44 04

Fax:+32 53 83 76 38
CALL CHEMTREC:
800.424.9300
OUTSIDE US:
202.483.7616
Pierce Milwaukee LLC
2202 N. Bartlett Avenue
Milwaukee, WI 53202-1009
USA
1.877.886.7629
7/3/2003
7/3/2003
Product name
Supplier
Manufacturer
Product No.
MSDS#
Validation Date
Print Date
In Case of Emergency
Section 1. Chemical Product and Company Identification
Responsible Name Pierce Administration
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Eng
1) TCEP.HCl
51805-45-9
10-20
Not available.
C
R34
Ingredient Name
EC Number
CAS No.
R-Phrases
Substance/Preparation
Preparation
%
Symbol
:
Section 2. Composition, Information on Ingredients
Physical/chemical hazards
Human health hazards
Environmental hazards Not applicable.
Causes burns.
Not applicable.
Absorbed through skin. Eye contact. Inhalation. Ingestion.
Emergency Overview
Medical Conditions Aggravated
by Overexposure:
Repeated or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or
prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection.
Not available.
Overexposure /Signs/Symptoms
Section 3. Hazards Identification
Routes of Entry
Potential Acute Health Effects
Carcinogenic Effects Data
See Toxicological Information (section 11)
Do not get in eyes, on skin or on clothing. Do not breathe vapor or mist. Keep container closed. Use only with
adequate ventilation. Wash thoroughly after handling.
Non-hazardous in case of ingestion. Non-hazardous in case of inhalation.
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
DANGER!
CAUSES RESPIRATORY TRACT, EYE AND SKIN BURNS.
Classification R34
United States
Europe
Continued on Next Page
TCEP
Page: 2/6
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.
Skin Contact
Ingestion
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Cold water may be used. Get medical attention immediately.
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing
and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical
attention immediately.
Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by coughing, choking, or
shortness of breath.
May be fatal if swallowed. May cause burns to mouth, throat, and stomach.
Irritation of the product in case of skin contact: Not available. Sensitization of the product: Not available.
Corrosive to skin on contact. Skin contact may produce burns.
Skin Contact
Corrosive to eyes.
Eye Contact
Inhalation
Aggravating conditions Repeated or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or
prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection.
First-Aid Measures
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention immediately.
Notes to Physician Not available.
Not available.
Protection of first-aiders
Ingestion
Effects and symptoms
Inhalation
Eye Contact
Section 4. First Aid Measures
Notice to Reader Get immediate medical attention.
Hazardous thermal (de)composition
products
Not applicable.
Non-flammable.
Not applicable.
Not applicable.
Not applicable.
Section 5. Fire Fighting Measures
Flammability of the Product
Flash Points
Fire Hazards in Presence of Various
Substances
Fire Fighting Media
and Instructions
Not applicable.
Protective Clothing (Fire)
Corrosive liquid.
Stop leak if without risk. Absorb with DRY earth, sand or other non-combustible material. Do not get water inside
container. Do not touch spilled material. Use water spray curtain to divert vapor drift. Prevent entry into sewers,
basements or confined areas; dike if needed. Call for assistance on disposal. Finish cleaning by spreading water on
the contaminated surface and allow to evacuate through the sanitary system.
Section 6. Accidental Release Measures
Small Spill and Leak Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container.
Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Environmental Precautions and
Clean-up Methods
Personal precautions Face shield. Full suit. Gloves (impervious). Boots.
Continued on Next Page
TCEP
Page: 3/6
Keep container tightly closed. Keep container in a cool, well-ventilated area.
Do not breathe vapor or mist. Keep container closed. Use only with adequate ventilation. Wash thoroughly after
handling.
Section 7. Handling and Storage
Handling
Storage
Suitable / Not suitable
Packaging materials
Use original container.
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
1) TCEP.HCl
Not available.
Germany
1) TCEP.HCl
Not available.
Netherlands
1) TCEP.HCl
Not available.
France
1) TCEP.HCl
Not available.
Norway
1) TCEP.HCl
Not available.
Denmark
1) TCEP.HCl
Not available.
Sweden
1) TCEP.HCl
Not available.
United States
Ingredient Name
Occupational Exposure Limits
Engineering Controls Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective threshold limit value.
Section 8. Exposure Controls/Personal Protection
Exposure Limit Values
Personal Protection
Eyes
Body
Hands
Protective Clothing
(Pictograms)
Gloves.
Lab coat.
Splash goggles.
Respiratory Respirator is not needed under normal and intended conditions of use, if exposures are kept below established limits.
Continued on Next Page
TCEP
Page: 4/6
The lowest known value is 100°C (212°F) (Milli-Q Water).
Liquid.
Neutral.
May start to solidify at -0.1°C (31.8°F) based on data for: Milli-Q Water.
The only known value is 1 (Water = 1) (Milli-Q Water).
The highest known value is 0.62 (Air = 1) (Milli-Q Water).
The highest known value is 2.3 kPa (@ 20°C) (Milli-Q Water).
See solubility in water.
Partially soluble in cold water, hot water.
Not applicable.
Not available.
Not available.
Not available.
Boiling/Condensation Point
Melting/Freezing Point
0.36 (Milli-Q Water) compared to Butyl acetate.
Physical State and
Appearance
Molecular Weight
pH (1% Soln/Water)
Specific Gravity
Vapor Pressure
Vapor Density
Evaporation Rate
Dispersion Properties
Solubility
Odor
Taste
Color
Section 9. Physical and Chemical Properties
The product is stable.
Slightly reactive to reactive with oxidizing agents, organic materials.
Will not occur.
Not available.
Section 10. Stability and Reactivity
Stability and Reactivity
Conditions to avoid
Materials to avoid
Hazardous Polymerization
Hazardous Decomposition
Products
Not applicable.
Acute oral toxicity (LD50): 23271 mg/kg (Rat) (Calculated value for the mixture).
Acute dermal toxicity (LD50): 20612 mg/kg (Rabbit) (Calculated value for the mixture).
Hazardous in case of eye contact (corrosive), of inhalation (lung corrosive).
Non-hazardous in case of inhalation. Non-irritant for lungs.
Not available.
Not available.
To the best of our knowledge, the toxicological properties of this product have not been thoroughly investigated.
(TCEP.HCl)
Not available.
Section 11. Toxicological Information
Toxicity to Animals
Chronic Effects on Humans
Other Toxic Effects on Humans
Special Remarks on Toxicity to
Animals
Special Remarks on Chronic
Effects on Humans
Special Remarks on Other Toxic
Effects on Humans
Ecotoxicity Not available.
Mobility
Germany water class
Not available.
Not available.
Not available.
Persistence/degradability
Bioaccumulative potential
VCI WGK: No products were found.
Section 12. Ecological Information
Continued on Next Page
TCEP
Page: 5/6
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Not available.
Waste Information
Waste Stream
Section 13. Disposal Considerations
Consult your local or regional authorities.
Contact the supplier for all information regarding the proper transportation method for this material.
Section 14. Transport Information
U.S. Federal Regulations
No products were found.
Corrosive
HCS Classification
Section 15. Regulatory Information
California prop. 65: No products were found.
TSCA 8(b) inventory: Milli-Q Water
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
State Regulations
CEPA DSL: Milli-Q Water
Australia (NICNAS): Milli-Q Water
Korea (TCCL): Milli-Q Water
Philippines (RA6969): Milli-Q Water
WHMIS (Canada) Not controlled under WHMIS (Canada).
R34- Causes burns.
DSCL (EEC)
International Regulations
Not available.
EINECS
International Lists
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found.
SARA 313 toxic chemical notification and release reporting: No products were found.
R34- Causes burns.
S1/2- Keep locked up and out of the reach of children.
S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37- Wear suitable protective clothing and gloves.
S39- Wear eye/face protection.
S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Corrosive
Label Requirements
(Europe)
1
Continued on Next Page
TCEP
Page: 6/6
Version
1
Date of Previous Issue No Previous
Validation
Not available.
Section 16. Other Information
References
Validated by Pierce Administration on 7/3/2003.
Verified by Pierce Administration.
Printed 7/3/2003.
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any
liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution.
Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
Hazardous Material
Information System
(U.S.A.)
2
0
0
0
0
2
National Fire Protection
Association (U.S.A.)
Health
Specific Hazard
Reactivity
Fire Hazard
Health
Fire Hazard
Reactivity
Personal Protection
History of Document Changes Any information changes since last document version are marked with a triangle symbol.
Causes burns.
Full text of R-Phrases
referenced under headings 2 and 3:
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Conforms to 93/112/EC and ISO 11014-1
Material Safety Data Sheet
Ammonium Bicarbonate
6773
89871D
In USA:
In Europe:
Pierce
Perbio Science
P.O. Box 117
Industriezone III
Rockford, IL 61105 Industrielaan 27
USA
9320 Erembodegem-Aalst
815.968.0747 or
Belgium
1.800.874.3723
Tel:+32 53 83 44 04

Fax:+32 53 83 76 38
CALL CHEMTREC:
800.424.9300
OUTSIDE US:
202.483.7616
Pierce Milwaukee LLC
2202 N. Bartlett Avenue
Milwaukee, WI 53202-1009
USA
1.877.886.7629
7/3/2003
7/3/2003
Product name
Supplier
Manufacturer
Product No.
MSDS#
Validation Date
Print Date
In Case of Emergency
Section 1. Chemical Product and Company Identification
Responsible Name Pierce Administration
Synonyms ACID AMMONIUM CARBONATE; AMMONIUM CARBONATE; AMMONIUM HYDROGEN CARBONATE; CARBONIC
ACID, MONOAMMONIUM SALT; MONOAMMONIUM CARBONATE; AMMONIUM BICARBONATE
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Eng
1) Ammonium Bicarbonate
1066-33-7
98-100
213-911-5
Xn
R22, R36/37/38
Ingredient Name
EC Number
CAS No.
R-Phrases
Substance/Preparation
Substance
%
Symbol
:
Section 2. Composition, Information on Ingredients
Physical/chemical hazards
Human health hazards
Environmental hazards Not applicable.
Harmful if ingested.
Irritating to eyes, respiratory system and skin.
Not applicable.
Absorbed through skin. Dermal contact. Eye contact. Inhalation. Ingestion.
Emergency Overview
Medical Conditions Aggravated
by Overexposure:
Repeated or prolonged exposure is not known to aggravate medical condition.
Not available.
Overexposure /Signs/Symptoms
Section 3. Hazards Identification
Routes of Entry
Potential Acute Health Effects
Carcinogenic Effects Data
Avoid contact with eyes, skin and clothing. Do not ingest. Avoid breathing dust. Keep container closed. Use only with
adequate ventilation. Wash thoroughly after handling.
Extremely hazardous in case of skin contact (irritant, permeator), of eye contact (irritant), of ingestion, of inhalation
(lung irritant). Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is
characterized by itching, scaling, reddening, or, occasionally, blistering.
CARCINOGENIC EFFECTS: Classified None., 4 (No evidence.) by NTP, None. by NIOSH, None..
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
DANGER!
CAUSES SEVERE RESPIRATORY TRACT, EYE AND SKIN IRRITATION.
MAY BE HARMFUL IF SWALLOWED.
Classification R22, R36/37/38
United States
Europe
Continued on Next Page
Ammonium Bicarbonate
Page: 2/6
See Toxicological Information (section 11)
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a
collar, tie, belt or waistband.
Skin Contact
Ingestion
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Cold water may be used. Get medical attention immediately.
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing
and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse. Thoroughly
clean shoes before reuse. Get medical attention immediately.
Extremely hazardous in case of inhalation (lung irritant).
Extremely hazardous in case of ingestion.
Extremely hazardous in case of skin contact (irritant, permeator). Skin inflammation is characterized by itching, scaling,
reddening, or, occasionally, blistering.
Skin Contact
Extremely hazardous in case of eye contact (irritant). Inflammation of the eye is characterized by redness, watering, and
itching.
Eye Contact
Inhalation
Aggravating conditions Repeated or prolonged exposure is not known to aggravate medical condition.
First-Aid Measures
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention immediately.
Notes to Physician Not available.
Not available.
Protection of first-aiders
Ingestion
Effects and symptoms
Inhalation
Eye Contact
Section 4. First Aid Measures
Notice to Reader Get immediate medical attention.
Hazardous thermal (de)composition
products
Not applicable.
Non-flammable.
Not applicable.
Not applicable.
Not applicable.
When heated to decomposition it emits toxic fumes.
Section 5. Fire Fighting Measures
Flammability of the Product
Flash Points
Fire Hazards in Presence of Various
Substances
Fire Fighting Media
and Instructions
Special Remarks on Fire Hazards
Not applicable.
Protective Clothing (Fire)
Use a shovel to put the material into a convenient waste disposal container. Be careful that the product is not present
at a concentration level above TLV. Check TLV on the MSDS and with local authorities.
Section 6. Accidental Release Measures
Small Spill and Leak Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading
water on the contaminated surface and dispose of according to local and regional authority requirements.
Environmental Precautions and
Clean-up Methods
Personal precautions Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Continued on Next Page
Ammonium Bicarbonate
Page: 3/6
Keep container tightly closed. Keep container in a cool, well-ventilated area.
Avoid contact with eyes, skin, and clothing. Do not ingest. Avoid breathing dust. Keep container closed. Use only
with adequate ventilation. Wash thoroughly after handling.
Section 7. Handling and Storage
Handling
Storage
Suitable / Not suitable
Packaging materials
Use original container.
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
1) Ammonium Bicarbonate
Not available.
Germany
1) Ammonium Bicarbonate
Not available.
Netherlands
1) Ammonium Bicarbonate
Not available.
France
1) Ammonium Bicarbonate
Not available.
Norway
1) Ammonium Bicarbonate
Not available.
Denmark
1) Ammonium Bicarbonate
Not available.
Sweden
1) Ammonium Bicarbonate
TWA: 2 STEL: 2 CEIL: 3 (mg/m3) from OSHA (PEL) [United States] [1991]
TWA: 3 STEL: 3 CEIL: 3 (ppb) from ACGIH (TLV) [United States] [1993]
United States
Ingredient Name
Occupational Exposure Limits
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Section 8. Exposure Controls/Personal Protection
Exposure Limit Values
Personal Protection
Eyes
Body
Hands
Protective Clothing
(Pictograms)
Gloves.
Lab coat.
Splash goggles.
Respiratory Respirator is not needed under normal and intended conditions of use, if exposures are kept below established limits.
Continued on Next Page
Ammonium Bicarbonate
Page: 4/6
Decomposes.
Solid.
10% (v/v). 100% (w/w).
7.8 [Basic.]
107.9°C (226.2°F)
1.5 (Water = 1)
See solubility in water.
Soluble in cold water, hot water.
Insoluble in methanol, acetone.
79.06 g/mole
Ammoniacal. (Slight.)
Not available.
White.
Boiling/Condensation Point
Melting/Freezing Point
Greater than 1. compared to Ether (anhydrous).
Dynamic: 10 cP
Physical State and
Appearance
Molecular Weight
pH (1% Soln/Water)
Specific Gravity
Volatility
Evaporation Rate
Viscosity
Dispersion Properties
Solubility
Odor
Taste
Color
NH4HCO3
Molecular Formula
10 (%)
VOC
Section 9. Physical and Chemical Properties
The product is stable.
Slightly reactive to reactive with oxidizing agents, acids.
Will not occur.
Not available.
Section 10. Stability and Reactivity
Stability and Reactivity
Conditions to avoid
Materials to avoid
Hazardous Polymerization
Hazardous Decomposition
Products
Not applicable.
LD50: Not available.
LC50: Not available.
Extremely hazardous in case of eye contact (irritant), of ingestion, of inhalation (lung irritant).
Very hazardous in case of eye contact (irritant), of ingestion, of inhalation (lung irritant).
CARCINOGENIC EFFECTS: Classified None., 4 (No evidence.) by NTP, None. by NIOSH, None..
Not available.
Material is irritating to mucous membranes and upper respiratory tract.
Not available.
Section 11. Toxicological Information
Toxicity to Animals
Chronic Effects on Humans
Other Toxic Effects on Humans
Special Remarks on Toxicity to
Animals
Special Remarks on Chronic
Effects on Humans
Special Remarks on Other Toxic
Effects on Humans
Continued on Next Page
Ammonium Bicarbonate
Page: 5/6
Ecotoxicity Not available.
Mobility
Germany water class
Not available.
Not available.
Not available.
Persistence/degradability
Bioaccumulative potential
VCI WGK: No products were found.
Section 12. Ecological Information
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Not available.
Waste Information
Waste Stream
Section 13. Disposal Considerations
Consult your local or regional authorities.
Contact the supplier for all information regarding the proper transportation method for this material.
Section 14. Transport Information
U.S. Federal Regulations
Irritating substance.
HCS Classification
Section 15. Regulatory Information
TSCA 8(b) inventory: Ammonium Bicarbonate
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: Ammonium Bicarbonate
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
WHMIS (Canada) CLASS D-2B: Material causing other toxic effects (TOXIC).
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Ammonium Bicarbonate
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Ammonium Bicarbonate: immediate health hazard
SARA 313 toxic chemical notification and release reporting: Ammonium Bicarbonate
R22- Harmful if swallowed.
R36/37/38- Irritating to eyes, respiratory system and skin.
S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39- Wear suitable protective clothing, gloves and eye/face protection.
S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where
possible).
Harmful
Label Requirements
(Europe)
1
Continued on Next Page
Ammonium Bicarbonate
Page: 6/6
Pennsylvania RTK: Ammonium Bicarbonate: (environmental hazard, generic environmental hazard)
Massachusetts RTK: Ammonium Bicarbonate
New Jersey: Ammonium Bicarbonate
California prop. 65: No products were found.
State Regulations
CEPA DSL: Ammonium Bicarbonate
Australia (NICNAS): Ammonium Bicarbonate
Korea (TCCL): Ammonium Bicarbonate
Philippines (RA6969): Ammonium Bicarbonate
R22- Harmful if swallowed.
R36/37/38- Irritating to eyes, respiratory system and skin.
DSCL (EEC)
International Regulations
Not available.
EINECS
International Lists
Version
1
Date of Previous Issue No Previous
Validation
-SAX, N.I. Dangerous Properties of Indutrial Materials. Toronto, Van Nostrand Reinold, 6e ed. 1984.
-The Sigma-Aldrich Library of Chemical Safety Data, Edition II.
-Hawley, G.G.. The Condensed Chemical Dictionary, 11e ed., New York N.Y., Van Nostrand Reinold, 1987.
Section 16. Other Information
References
Validated by Pierce Administration on 7/3/2003.
Verified by Pierce Administration.
Printed 7/3/2003.
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any
liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution.
Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
Hazardous Material
Information System
(U.S.A.)
2
0
0
E
0
0
2
National Fire Protection
Association (U.S.A.)
Health
Specific Hazard
Reactivity
Fire Hazard
Health
Fire Hazard
Reactivity
Personal Protection
History of Document Changes Any information changes since last document version are marked with a triangle symbol.
Harmful if ingested.
Irritating to eyes, respiratory system and skin.
Full text of R-Phrases
referenced under headings 2 and 3:
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Conforms to 93/112/EC and ISO 11014-1
Material Safety Data Sheet
Acetonitrile
6772
89871C
In USA:
In Europe:
Pierce
Perbio Science
P.O. Box 117
Industriezone III
Rockford, IL 61105 Industrielaan 27
USA
9320 Erembodegem-Aalst
815.968.0747 or
Belgium
1.800.874.3723
Tel:+32 53 83 44 04

Fax:+32 53 83 76 38
CALL CHEMTREC:
800.424.9300
OUTSIDE US:
202.483.7616
Pierce Milwaukee LLC
2202 N. Bartlett Avenue
Milwaukee, WI 53202-1009
USA
1.877.886.7629
7/25/2003
7/25/2003
Product name
Supplier
Manufacturer
Product No.
MSDS#
Validation Date
Print Date
In Case of Emergency
Section 1. Chemical Product and Company Identification
Responsible Name Pierce Administration
Synonyms ACETONITRIL (GERMAN, DUTCH); ACETONITRILE ; CYANOMETHANE; CYANURE DE METHYL (FRENCH);
ETHANENITRILE; ETHYL NITRILE; METHANECARBONITRILE; METHANE, CYANO-; METHYL CYANIDE;
NCI-C60822; USAF EK-488
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Eng
1) Acetonitrile
75-05-8
98-100
200-835-2
F, T
R11, R23/24/25
Ingredient Name
EC Number
CAS No.
R-Phrases
Substance/Preparation
Substance
%
Symbol
:
Section 2. Composition, Information on Ingredients
Absorbed through skin. Eye contact. Inhalation. Ingestion.
Emergency Overview
Medical Conditions Aggravated
by Overexposure:
Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or
many human organs.
Not available.
Overexposure /Signs/Symptoms
Section 3. Hazards Identification
Routes of Entry
Potential Acute Health Effects
Carcinogenic Effects Data
Keep away from heat, sparks and flame. Avoid contact with eyes, skin and clothing. Do not ingest. Avoid breathing
vapor or mist. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling.
Very hazardous in case of eye contact (irritant). Hazardous in case of skin contact (irritant). Slightly hazardous in case
of skin contact (permeator), of ingestion, of inhalation (lung irritant). Severe over-exposure can result in death.
Inflammation of the eye is characterized by redness, watering, and itching.
CARCINOGENIC EFFECTS: Classified None. by NIOSH. A4 (Not classifiable for human or animal.) by ACGIH.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
WARNING!
HIGHLY FLAMMABLE LIQUID AND VAPOR.
VAPOR MAY CAUSE FLASH FIRE.
HARMFUL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED.
CAUSES SEVERE EYE IRRITATION.
CAUSES DAMAGE TO THE FOLLOWING ORGANS: KIDNEYS, LIVER, MUCOUS
MEMBRANES, CARDIOVASCULAR SYSTEM, RESPIRATORY TRACT, SKIN, EYES,
CENTRAL NERVOUS SYSTEM, EYE, LENS OR CORNEA.
MAY CAUSE SKIN IRRITATION.
United States
Continued on Next Page
Acetonitrile
Page: 2/6
Physical/chemical hazards
Human health hazards
Environmental hazards Not applicable.
Toxic by inhalation, in contact with skin and if swallowed.
Highly flammable.
See Toxicological Information (section 11)
Classification R11, R23/24/25
Europe
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately.
Skin Contact
Ingestion
Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping
eyelids open. Cold water may be used. Get medical attention immediately.
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing
and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse. Thoroughly
clean shoes before reuse. Get medical attention immediately.
May be fatal if inhaled.
May be fatal if swallowed.
Hazardous in case of skin contact (irritant). Slightly hazardous in case of skin contact (permeator). Severe over-exposure
can result in death. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering.
Skin Contact
Very hazardous in case of eye contact (irritant). Inflammation of the eye is characterized by redness, watering, and itching.
Eye Contact
Inhalation
Aggravating conditions Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many
human organs.
First-Aid Measures
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention immediately.
Notes to Physician Not available.
Not available.
Protection of first-aiders
Ingestion
Effects and symptoms
Inhalation
Eye Contact
Section 4. First Aid Measures
Notice to Reader Get immediate medical attention.
Hazardous thermal (de)composition
products
Not available.
Flammable.
CLOSED CUP: 5.9°C (42.6°F). OPEN CUP: 5.6°C (42.1°F) (Cleveland).
Flammable liquid, soluble or dispersed in water.
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use alcohol foam, water spray or fog.
Highly flammable in presence of open flames and sparks, of heat, of oxidizing materials.
Store under nitrogen.
Section 5. Fire Fighting Measures
Flammability of the Product
Flash Points
Fire Hazards in Presence of Various
Substances
Fire Fighting Media
and Instructions
Special Remarks on Fire Hazards
Be sure to use an approved/certified respirator or equivalent.
Protective Clothing (Fire)
Continued on Next Page
Acetonitrile
Page: 3/6
Flammable liquid. Poisonous liquid.
Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth, sand or
other non-combustible material. Do not get water inside container. Do not touch spilled material. Use water spray to
reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Call for assistance on
disposal. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDS and
with local authorities.
Section 6. Accidental Release Measures
Small Spill and Leak Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container.
Environmental Precautions and
Clean-up Methods
Personal precautions Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly
closed and sealed until ready for use. Avoid all possible sources of ignition (spark or flame).
Keep away from heat, sparks and flame. Keep container closed. Use only with adequate ventilation. To avoid fire or
explosion, dissipate static electricity during transfer by grounding and bonding containers and equipment before
transferring material. Use explosion-proof electrical (ventilating, lighting and material handling) equipment.
Section 7. Handling and Storage
Handling
Storage
Suitable / Not suitable
Packaging materials
Use original container.
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
1) Acetonitrile
TWA: 40 STEL: 60 CEIL: 160 (ppm) from BAuA [Germany] [1999] SKIN
Germany
1) Acetonitrile
TWA: 40 (ppm) from Arbeidsinspectie [Netherlands] [2000] Inhalation
Netherlands
1) Acetonitrile
TWA: 40 (ppm) from INRS [France] [1999] SKIN
France
1) Acetonitrile
TWA: 30 STEL: 105 (ppm) from Arbeidstilsynet [Norway] [1996] Inhalation
Norway
1) Acetonitrile
TWA: 40 (ppm) from Arbejdstilsynet [Denmark] [1996] Inhalation
Denmark
1) Acetonitrile
TWA: 30 STEL: 100 CEIL: 60 (ppm) from AFS [Sweden] [1996] Inhalation
Sweden
1) Acetonitrile
TWA: 40 STEL: 60 (ppm) from ACGIH (TLV) [United States] [2000] Inhalation
TWA: 40 STEL: 60 (ppb) from OSHA (PEL) [United States] [1989] Inhalation
United States
Ingredient Name
Occupational Exposure Limits
Engineering Controls Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station
location.
Section 8. Exposure Controls/Personal Protection
Exposure Limit Values
Personal Protection
Eyes
Body Lab coat.
Splash goggles.
Continued on Next Page
Acetonitrile
Page: 4/6
Hands
Protective Clothing
(Pictograms)
Gloves.
Respiratory Respirator is not needed under normal and intended conditions of use, if exposures are kept below established limits.
81.72°C (179.1°F)
Liquid.
7 [Neutral.]
-41.85°C (-43.3°F)
0.787 (Water = 1)
1.42 (Air = 1)
9.7 kPa (@ 20°C)
See solubility in water, methanol.
Soluble in cold water, hot water, methanol.
40 ppm
274.8°C (526.6°F)
41.05 g/mole
Ethereal.
COLORLESS LIQUID WITH A SWEET,
ETHER-LIKE ODOR [NOTE:FORMS
CYANIDE IN THE BODY] Sweet.
Colorless.
Boiling/Condensation Point
Melting/Freezing Point
2.33 compared to (n-BUTYL ACETATE=1)
Dynamic: 0.35 cP
Physical State and
Appearance
Molecular Weight
pH (1% Soln/Water)
Critical Temperature
Specific Gravity
Vapor Pressure
Vapor Density
Odor Threshold
Evaporation Rate
Viscosity
Dispersion Properties
Solubility
Odor
Taste
Color
Section 9. Physical and Chemical Properties
The product is stable.
Reactive with oxidizing agents, acids, moisture.
Slightly reactive to reactive with reducing agents, alkalis.
Will not occur.
Not available.
Section 10. Stability and Reactivity
Stability and Reactivity
Conditions to avoid
Materials to avoid
Hazardous Polymerization
Hazardous Decomposition
Products
Not available.
Acute oral toxicity (LD50): 50 mg/kg [Rabbit].
Acute dermal toxicity (LD50): 982 mg/kg [Rabbit.].
Acute toxicity of the vapor (LC50): 16000 ppm 4 hours [Rat.].
Slightly hazardous in case of ingestion, of inhalation (lung irritant).
CARCINOGENIC EFFECTS: Classified None. by NIOSH. A4 (Not classifiable for human or animal.) by ACGIH.
Causes damage to the following organs: kidneys, liver, mucous membranes, cardiovascular system, upper respiratory tract,
skin, eyes, central nervous system (CNS), eye, lens or cornea.
Not available.
Section 11. Toxicological Information
Toxicity to Animals
Chronic Effects on Humans
Other Toxic Effects on Humans
Special Remarks on Toxicity to
Animals
Continued on Next Page
Acetonitrile
Page: 5/6
Material is irritating to mucous membranes and upper respiratory tract.
Not available.
Special Remarks on Chronic
Effects on Humans
Special Remarks on Other Toxic
Effects on Humans
Ecotoxicity Not available.
Mobility
Germany water class
Not available.
Not available.
Not available.
Persistence/degradability
Bioaccumulative potential
VCI WGK: No products were found.
Section 12. Ecological Information
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Not available.
Waste Information
Waste Stream
Section 13. Disposal Considerations
Consult your local or regional authorities.
Contact the supplier for all information regarding the proper transportation method for this material.
Section 14. Transport Information
U.S. Federal Regulations
Flammable liquid having a flash point lower than 37.8°C (100°F).
Toxic.
Irritating substance.
Warning: This product contains a chemical known to the State of California to cause cancer.
HCS Classification
Section 15. Regulatory Information
TSCA 8(a) PAIR: Acetonitrile
TSCA 8(b) inventory: Acetonitrile
TSCA 8(c) calls for record of SAR: Acetonitrile
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Acetonitrile
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Acetonitrile: fire, immediate health hazard, delayed health hazard
R11- Highly flammable.
R23/24/25- Toxic by inhalation, in contact with skin and if swallowed.
S16- Keep away from sources of ignition - No smoking.
S27- Take off immediately all contaminated clothing.
S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where
possible).
Highly flammable, Toxic
Label Requirements
(Europe)
1
Continued on Next Page
Acetonitrile
Page: 6/6
Pennsylvania RTK: Acetonitrile: (environmental hazard, generic environmental hazard)
Massachusetts RTK: Acetonitrile
New Jersey: Acetonitrile
California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which
would require a warning under the statute: Acetonitrile
Clean Water Act (CWA) 307: Acetonitrile
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
State Regulations
CEPA DSL: Acetonitrile
Australia (NICNAS): Acetonitrile
Germany water class: Acetonitrile
VCI WGK: No products were found.
Korea (TCCL): Acetonitrile
Philippines (RA6969): Acetonitrile
WHMIS (Canada) CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F).
CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC).
R11- Highly flammable.
R23/24/25- Toxic by inhalation, in contact with skin and if swallowed.
DSCL (EEC)
International Regulations
Not available.
EINECS
International Lists
SARA 313 toxic chemical notification and release reporting: Acetonitrile
Version
2.01
Date of Previous Issue
7/23/2003
-SAX, N.I. Dangerous Properties of Industrial Materials. Toronto, Van Nostrand Reinold, 6e ed. 1984. -The
Sigma-Aldrich Library of Chemical Safety Data, Edition II.
Section 16. Other Information
References
Validated by Pierce Administration on 7/25/2003.
Verified by Pierce Administration.
Printed 7/25/2003.
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any
liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution.
Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
Hazardous Material
Information System
(U.S.A.)
2
3
0
h
0
3
2
*
National Fire Protection
Association (U.S.A.)
Health
Specific Hazard
Reactivity
Fire Hazard
Health
Fire Hazard
Reactivity
Personal Protection
History of Document Changes Any information changes since last document version are marked with a triangle symbol.
Toxic by inhalation, in contact with skin and if swallowed.
Full text of R-Phrases
referenced under headings 2 and 3:
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Conforms to 93/112/EC and ISO 11014-1
Material Safety Data Sheet
Iodoacetamide
6775
89871F
In USA:
In Europe:
Pierce
Perbio Science
P.O. Box 117
Industriezone III
Rockford, IL 61105 Industrielaan 27
USA
9320 Erembodegem-Aalst
815.968.0747 or
Belgium
1.800.874.3723
Tel:+32 53 83 44 04

Fax:+32 53 83 76 38
CALL CHEMTREC:
800.424.9300
OUTSIDE US:
202.483.7616
Pierce Milwaukee LLC
2202 N. Bartlett Avenue
Milwaukee, WI 53202-1009
USA
1.877.886.7629
7/3/2003
7/3/2003
Product name
Supplier
Manufacturer
Product No.
MSDS#
Validation Date
Print Date
In Case of Emergency
Section 1. Chemical Product and Company Identification
Responsible Name Pierce Administration
Synonyms
IODOACETAMIDE; ALPHA-IODOACETAMIDE; 2-IODOACETAMIDE; MONOIODOACETAMIDE; SURAUTO; USAF
D-1
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Eng
1) Iodoacetamide
144-48-9
98-100
205-630-1
T
R23/24/25, R42/43,
R61
Ingredient Name
EC Number
CAS No.
R-Phrases
Substance/Preparation
Substance
%
Symbol
:
Section 2. Composition, Information on Ingredients
Absorbed through skin. Eye contact. Inhalation. Ingestion.
Emergency Overview
Medical Conditions Aggravated
by Overexposure:
Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or
many human organs.
Not available.
Overexposure /Signs/Symptoms
Section 3. Hazards Identification
Routes of Entry
Potential Acute Health Effects
Carcinogenic Effects Data
Avoid contact with eyes, skin and clothing. Do not ingest. Do not breathe dust. Avoid prolonged or repeated contact
with skin. Keep container closed. Use only with adequate ventilation. Avoid exposure during pregnancy. Wash
thoroughly after handling.
Hazardous in case of skin contact (sensitizer), of inhalation (lung sensitizer). Severe over-exposure can result in
death.
CARCINOGENIC EFFECTS: Classified None. by NIOSH.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
WARNING!
HARMFUL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED.
CAUSES DAMAGE TO THE FOLLOWING ORGANS: MUCOUS MEMBRANES, SKIN,
EYES, thyroid.
POSSIBLE BIRTH DEFECT HAZARD.
CONTAINS MATERIAL WHICH MAY CAUSE BIRTH DEFECTS BASED ON ANIMAL
DATA.
MAY CAUSE ALLERGIC RESPIRATORY AND SKIN REACTION.
United States
Europe
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Iodoacetamide
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Physical/chemical hazards
Human health hazards
Environmental hazards Not applicable.
Toxic by inhalation, in contact with skin and if swallowed.
May cause sensitization by inhalation and skin contact.
May cause harm to the unborn child.
Not applicable.
See Toxicological Information (section 11)
Classification R23/24/25, R42/43, R61
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately.
Skin Contact
Ingestion
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical attention.
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately.
May be fatal if inhaled.
May be fatal if swallowed.
Hazardous in case of skin contact (sensitizer). Severe over-exposure can result in death.
Skin Contact
Not available.
Eye Contact
Inhalation
Aggravating conditions Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many
human organs.
First-Aid Measures
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention immediately.
Notes to Physician Not available.
Not available.
Protection of first-aiders
Ingestion
Effects and symptoms
Inhalation
Eye Contact
Section 4. First Aid Measures
Notice to Reader Get immediate medical attention.
Hazardous thermal (de)composition
products
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.
May be combustible at high temperature.
Not available.
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Not available.
Section 5. Fire Fighting Measures
Flammability of the Product
Flash Points
Fire Hazards in Presence of Various
Substances
Fire Fighting Media
and Instructions
Be sure to use an approved/certified respirator or equivalent.
Protective Clothing (Fire)
Poisonous solid.
Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to reduce
vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition sources. Call for
assistance on disposal.
Section 6. Accidental Release Measures
Small Spill and Leak Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Environmental Precautions and
Clean-up Methods
Personal precautions Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
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Keep container tightly closed. Keep container in a cool, well-ventilated area.
Avoid contact with eyes, skin, and clothing. Do not ingest. Do not breathe dust. Avoid prolonged or repeated contact
with skin. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling.
Section 7. Handling and Storage
Handling
Storage
Suitable / Not suitable
Packaging materials
Use original container.
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
1) Iodoacetamide
Not available.
Germany
1) Iodoacetamide
Not available.
Netherlands
1) Iodoacetamide
Not available.
France
1) Iodoacetamide
Not available.
Norway
1) Iodoacetamide
Not available.
Denmark
1) Iodoacetamide
Not available.
Sweden
1) Iodoacetamide
Not available.
United States
Ingredient Name
Occupational Exposure Limits
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Section 8. Exposure Controls/Personal Protection
Exposure Limit Values
Personal Protection
Eyes
Body
Hands
Protective Clothing
(Pictograms)
Gloves.
Lab coat.
Splash goggles.
Respiratory Respirator is not needed under normal and intended conditions of use, if exposures are kept below established limits.
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Iodoacetamide
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Solid.
93.06 to 96.06°C (199.5 to 204.9°F)
Not available.
Not available.
184.97 g/mole
Not available.
Not available.
Not available.
Melting/Freezing Point
Physical State and
Appearance
Molecular Weight
Dispersion Properties
Solubility
Odor
Taste
Color
C2 H4 I N O
Molecular Formula
Section 9. Physical and Chemical Properties
The product is stable.
Reactive with oxidizing agents, reducing agents, acids, alkalis.
Will not occur.
Not available.
Section 10. Stability and Reactivity
Stability and Reactivity
Conditions to avoid
Materials to avoid
Hazardous Polymerization
Hazardous Decomposition
Products
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.
Acute oral toxicity (LD50): 74 mg/kg [Mouse].
Hazardous in case of inhalation (lung sensitizer).
CARCINOGENIC EFFECTS: Classified None. by NIOSH.
Causes damage to the following organs: mucous membranes, skin, eyes, thyroid.
Not available.
Not available.
Not available.
Section 11. Toxicological Information
Toxicity to Animals
Chronic Effects on Humans
Other Toxic Effects on Humans
Special Remarks on Toxicity to
Animals
Special Remarks on Chronic
Effects on Humans
Special Remarks on Other Toxic
Effects on Humans
Ecotoxicity Not available.
Mobility
Germany water class
Not available.
Not available.
Not available.
Persistence/degradability
Bioaccumulative potential
VCI WGK: No products were found.
Section 12. Ecological Information
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Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Not available.
Waste Information
Waste Stream
Section 13. Disposal Considerations
Consult your local or regional authorities.
Contact the supplier for all information regarding the proper transportation method for this material.
Section 14. Transport Information
U.S. Federal Regulations
Toxic.
Sensitizing substance.
HCS Classification
Section 15. Regulatory Information
TSCA 8(b) inventory: Iodoacetamide
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
CEPA DSL: Iodoacetamide
WHMIS (Canada) CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
R23/24/25- Toxic by inhalation, in contact with skin and if swallowed.
R42/43- May cause sensitization by inhalation and skin contact.
R61- May cause harm to the unborn child.
DSCL (EEC)
International Regulations
Not available.
EINECS
International Lists
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Iodoacetamide
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Iodoacetamide: delayed health hazard
SARA 313 toxic chemical notification and release reporting: No products were found.
R23/24/25- Toxic by inhalation, in contact with skin and if swallowed.
R42/43- May cause sensitization by inhalation and skin contact.
R61- May cause harm to the unborn child.
S22- Do not breathe dust.
S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39- Wear suitable protective clothing, gloves and eye/face protection.
S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where
possible).
Toxic
Label Requirements
(Europe)
1
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Iodoacetamide
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No products were found.
California prop. 65: No products were found.
State Regulations
Australia (NICNAS): Iodoacetamide
VCI WGK: No products were found.
Korea (TCCL): Iodoacetamide
Philippines (RA6969): Iodoacetamide
Version
1
Date of Previous Issue No Previous
Validation
Not available.
Section 16. Other Information
References
Validated by Pierce Administration on 7/3/2003.
Verified by Pierce Administration.
Printed 7/3/2003.
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any
liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution.
Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
Hazardous Material
Information System
(U.S.A.)
2
0
0
E
0
0
2
*
National Fire Protection
Association (U.S.A.)
Health
Specific Hazard
Reactivity
Fire Hazard
Health
Fire Hazard
Reactivity
Personal Protection
History of Document Changes Any information changes since last document version are marked with a triangle symbol.
Toxic by inhalation, in contact with skin and if swallowed.
May cause sensitization by inhalation and skin contact.
May cause harm to the unborn child.
Full text of R-Phrases
referenced under headings 2 and 3:
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.