Microfabricated Tissue Models (MTM) Lab
Fabricates Novel 3D Liver Micro-Tissue
The MTM Lab, an award-
winning microfabricated tissue
models research lab, releases
cutting-edge innovations in the
field of cell & tissue engineering.
Striving for transformative
impact, the Lab creates
engineered tissue for
applications in developing drugs,
modeling diseases and
enhancing regenerative
medicine.
The microfabricated tissues
and cells are used to
understand the underlying
mechanisms of diseases in
order to improve treatments
and outcomes.
According to Dr Salman Khetani, Lab
Director, the most significant development is
" the fabrication of a novel 3D liver micro-
tissue using a technique called droplet
microfluidics that allows precise control over
the interactions between cells and their
surrounding protein matrix.
" The human liver cells in these
microtissues function for 7 weeks and
are useful for several applications,
including drug toxicity testing,
understanding liver diseases such as
non-alcoholic fatty liver disease and
alcoholic fatty liver disease.
These liver diseases affect
nearly a third of the US
population, and there is
currently no known cure.
Liver cells, also known as
hepatocytes, are fundamental
components of the liver, an organ
renowned for its multifaceted role
in metabolic processes and
detoxification within the human
body.
"We strive to aid in
developing a cure for these
widespread liver diseases",
says Dr Salman Khetani.
"The growth of our Lab has
been tremendous over the
past few years, but
especially in 2023", says Dr
Salman Khetani.
The latest development in the Lab
is an expanding the repertoire to
stem cell-derived cardiomyoctes
in order to better understand the
underlying mechanisms of various
heart diseases.
Find Out More At
https://www.mtmlabor
atory.com